Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Heptanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 50 mg/kg bw/day | oral | rabbit | Subchronic | COSMOS_DB |
| dose_tested | 50 mg/kg bw/day | oral | rabbit | Subchronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Skin and eye irritant; respiratory irritant at high concentrations; RIFM-assessed analogs indicate safe fragrance use at declared levels; concentration-dependent safety profile
Regulatory Flags
Frequently Asked Questions
Is Heptanol safe in cosmetics?
Skin and eye irritant; respiratory irritant at high concentrations; RIFM-assessed analogs indicate safe fragrance use at declared levels; concentration-dependent safety profile The EU classifies Heptanol as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Heptanol allowed in the EU?
Heptanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptanol do in cosmetics?
Heptanol functions as: Fragrance, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 111-70-6.
What is the Margin of Safety for Heptanol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Heptanol?
The NOAEL (No Observed Adverse Effect Level) for Heptanol is 50 mg/kg bw/day based on a Subchronic study via oral route in rabbit. A total of 4 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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