Hexadecalactone

INCI: HEXADECALACTONE

CAS Number
| 6. Hexacosyl glycol
Function
Fragrance
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

IFRA unrestricted in all product categories; classified as irritant on SDS at neat concentration, but at typical fragrance incorporation levels (0.01โ€“0.1%) this is not a concern; environmentally, macrocyclic musks and lactones should be monitored for aquatic persistence

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Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Hexadecalactone safe in cosmetics?

IFRA unrestricted in all product categories; classified as irritant on SDS at neat concentration, but at typical fragrance incorporation levels (0.01โ€“0.1%) this is not a concern; environmentally, macrocyclic musks and lactones should be monitored for aquatic persistence The EU classifies Hexadecalactone as "permitted". Safety rating: EXCELLENT.

Is Hexadecalactone allowed in the EU?

Hexadecalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexadecalactone do in cosmetics?

Hexadecalactone functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: | 6. Hexacosyl glycol.

What is the Margin of Safety for Hexadecalactone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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