Is Hexadecene safe in cosmetics?
Hexadecene has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hexadecene
Also known as: EINECS 211-105-8, Gulftene 16, UNII-97T015M2UX, 1-Cetene, Cetene (+4 more)
INCI: HEXADECENE
Hexadecene (CAS 629-73-2) is a cosmetic cosmetic ingredient functioning as Emollient, skin-conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 629-73-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Hexadecene is classified GHS Danger (H304, H410) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Emollient, skin-conditioning agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
hexadec-1-ene
InChIKey
GQEZCXVZFLOKMC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexadecene.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Solubility enhancer
Expert Verdict
Expert safety assessment and concern-level summary for Hexadecene.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Hexadecene by CAS number or substance name.
Studies
16
Lowest NOAEL
101 mg/kg bw/day
Highest NOAEL
1010 mg/kg bw/day
ToxValDB_ECHA_IUCLID
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
EINECS 211-105-8
Gulftene 16
UNII-97T015M2UX
1-Cetene
Cetene
Cetylene
Hexadecylene-1
alpha-Hexadecene
alpha-Hexadecylene
Chemical Function
Solubility enhancer
Dye
Regulatory Lists
air; detected; emissions; Europe; Toys and children's products
fracking; water
air; detected; emissions; Europe; Toys and children's products
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182381
Frequently Asked Questions
Is Hexadecene allowed in the EU?
Hexadecene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexadecene do in cosmetics?
Hexadecene functions as: Emollient, skin-conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 629-73-2.
Is Hexadecene used outside cosmetics?
Hexadecene also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Hexadecene have different safety status in cosmetics vs industrial chemicals?
Hexadecene is classified GHS Danger (H304, H410) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Hexadecene compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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