Is Hexyltrimethoxysilane safe in cosmetics?
Hexyltrimethoxysilane has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hexyltrimethoxysilane
Also known as: Silane, hexyltrimethoxy-, EINECS 221-331-9, UNII-9AUI936HIC
INCI: HEXYLTRIMETHOXYSILANE
Hexyltrimethoxysilane (CAS 3069-19-0) is a cosmetic cosmetic ingredient functioning as Surface modifier / hair and skin conditioning (silane-based hydrophobic coating. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3069-19-0 →
Auto-generated CPSR Part A draft with source citations
Function
Surface modifier / hair and skin conditioning (silane-based hydrophobic coating agent)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
hexyl(trimethoxy)silane
InChIKey
CZWLNMOIEMTDJY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not specifically restricted under 21 CFR; listed on EPA TSCA inventory
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyltrimethoxysilane.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter
Chemical reaction regulator
Softener and conditioner
Surface modifier
Wetting agent (non-aqueous)
Expert Verdict
Expert safety assessment and concern-level summary for Hexyltrimethoxysilane.
Known Synonyms
Silane, hexyltrimethoxy-
EINECS 221-331-9
UNII-9AUI936HIC
Chemical Function
Softener and conditioner
Chemical reaction regulator
Adhesion/cohesion promoter
Wetting agent (non-aqueous)
Surface modifier
Frequently Asked Questions
Is Hexyltrimethoxysilane allowed in the EU?
Hexyltrimethoxysilane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyltrimethoxysilane do in cosmetics?
Hexyltrimethoxysilane functions as: Surface modifier / hair and skin conditioning (silane-based hydrophobic coating agent). It is classified as a cosmetic ingredient in our database. CAS number: 3069-19-0.
Is Hexyltrimethoxysilane used outside cosmetics?
Hexyltrimethoxysilane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyltrimethoxysilane compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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