Excellent Cosmetic Ingredient NOAEL Data

Hydrogenated Polydecene

INCI: HYDROGENATED POLYDECENE

Hydrogenated Polydecene (CAS 68037-01-4) is a cosmetic cosmetic ingredient functioning as Emollient, Hair conditioning agent, Skin-conditioning agent, Solvent. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 68037-01-4 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, Hair conditioning agent, Skin-conditioning agent, Solvent
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
500-183-1

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR concluded safe in cosmetics in present practices of use and concentration (2020).

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrogenated Polydecene.

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Toxicological Studies

5 study endpoints found for Hydrogenated Polydecene. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat chronic ToxValDB_ECHA_IUCLID
NOAEL =4159.4 mg/kg bw/day oral Rat subchronic ToxValDB_ECHA_IUCLID
NOAEL =4619.9 mg/kg bw/day oral Rat subchronic ToxValDB_ECHA_IUCLID
NOAEL =6245 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID
NOAEL =6771 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

1 property record from structured ingredient metadata.

concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "10.0", "typical_concentration_pct": "5.0", "product_type": "Moisturizer", "function_at_concentration": "Emollient, occlusive", "source": "CIR Safety Assessment"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer Fragrance Softener and conditioner Solvent

Expert Verdict

Expert safety assessment and concern-level summary for Hydrogenated Polydecene.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Hydrogenated Polydecene by CAS number or substance name.

Studies
5
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
6771 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Solvent Softener and conditioner Deodorizer Fragrance

Regulatory Lists

Europe; Personal care - make-up and related Europe; Personal care - make-up and related

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Hydrogenated Polydecene safe in cosmetics?

Hydrogenated Polydecene has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 5 toxicological study endpoint(s) are available in our database.

Is Hydrogenated Polydecene allowed in the EU?

Hydrogenated Polydecene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Polydecene do in cosmetics?

Hydrogenated Polydecene functions as: Emollient, Hair conditioning agent, Skin-conditioning agent, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 68037-01-4.

What is the NOAEL for Hydrogenated Polydecene?

The NOAEL (No Observed Adverse Effect Level) for Hydrogenated Polydecene is =1000 mg/kg bw/day based on a chronic study via oral route in Rat. A total of 5 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Hydrogenated Polydecene used outside cosmetics?

Hydrogenated Polydecene also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Hydrogenated Polydecene have different safety status in cosmetics vs industrial chemicals?

Hydrogenated Polydecene is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.

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