Hydroxydichlorodiphenyl Ether (Diclosan)

INCI: HYDROXYDICHLORODIPHENYL ETHER

CAS Number
3380-30-1
Function
Antimicrobial / preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.3%
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted in cosmetics under 21 CFR; however, FDA increased scrutiny on chlorinated antimicrobials post-2016 triclosan rule

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Causes serious eye damage; chlorinated structure raises environmental persistence concerns; structurally related to triclosan which is banned in OTC antiseptic washes in the US.

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Concern Level: High

Regulatory Flags

preservative

Frequently Asked Questions

Is Hydroxydichlorodiphenyl Ether (Diclosan) safe in cosmetics?

Causes serious eye damage; chlorinated structure raises environmental persistence concerns; structurally related to triclosan which is banned in OTC antiseptic washes in the US. The EU classifies Hydroxydichlorodiphenyl Ether (Diclosan) as "restricted". Safety rating: MODERATE.

Is Hydroxydichlorodiphenyl Ether (Diclosan) allowed in the EU?

Hydroxydichlorodiphenyl Ether (Diclosan) EU regulatory status: restricted. Maximum allowed concentration: 0.3%. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxydichlorodiphenyl Ether (Diclosan) do in cosmetics?

Hydroxydichlorodiphenyl Ether (Diclosan) functions as: Antimicrobial / preservative. It is classified as a cosmetic ingredient in our database. CAS number: 3380-30-1.

What is the Margin of Safety for Hydroxydichlorodiphenyl Ether (Diclosan)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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