Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Pharmaceutical-grade ingredient with reproductive toxicity risk and anaphylactoid reactions reported; contains sodium iodide, contraindicated for iodine-sensitive individuals; not appropriate for cosmetic formulation.
Regulatory Flags
Frequently Asked Questions
Is Indocyanine Green safe in cosmetics?
Pharmaceutical-grade ingredient with reproductive toxicity risk and anaphylactoid reactions reported; contains sodium iodide, contraindicated for iodine-sensitive individuals; not appropriate for cosmetic formulation. The EU classifies Indocyanine Green as "permitted". Safety rating: POOR.
Is Indocyanine Green allowed in the EU?
Indocyanine Green EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Indocyanine Green do in cosmetics?
Indocyanine Green functions as: Colorant, diagnostic dye. It is classified as a cosmetic ingredient in our database. CAS number: 3599-32-4 / EC 222-751-5.
What is the Margin of Safety for Indocyanine Green?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Indocyanine Green compliance across multiple jurisdictions:
Related Ingredients
Is Indocyanine Green in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Indocyanine Green in your formulation.