Isoamyl p-Methoxycinnamate

INCI: ISOAMYL P-METHOXYCINNAMATE

CAS Number
71617-10-2 [^1_6]
Function
UV filter; UV absorber; light stabilizer
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 10%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not approved as an OTC sunscreen active under 21 CFR 352; may be used as a non-active cosmetic ingredient at low levels

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contact allergy risk due to cinnamate cross-reactivity; potential photoinstability under prolonged UV exposure reducing efficacy. Not FDA-approved as sunscreen active in the US. Requires concentration compliance and labeling per EU Annex VI.

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Concern Level: Moderate

Frequently Asked Questions

Is Isoamyl p-Methoxycinnamate safe in cosmetics?

Contact allergy risk due to cinnamate cross-reactivity; potential photoinstability under prolonged UV exposure reducing efficacy. Not FDA-approved as sunscreen active in the US. Requires concentration compliance and labeling per EU Annex VI. The EU classifies Isoamyl p-Methoxycinnamate as "restricted". Safety rating: MODERATE.

Is Isoamyl p-Methoxycinnamate allowed in the EU?

Isoamyl p-Methoxycinnamate EU regulatory status: restricted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoamyl p-Methoxycinnamate do in cosmetics?

Isoamyl p-Methoxycinnamate functions as: UV filter; UV absorber; light stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 71617-10-2 [^1_6].

What is the Margin of Safety for Isoamyl p-Methoxycinnamate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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