Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Amiloxate (Isoamyl p-Methoxycinnamate). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.200 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | >=0.9 other | oral | rat | oral | REACH |
Expert Verdict
Good safety profile within approved limits. Restricted in EU with 25% maximum concentration; not permitted in the US.
Regulatory Flags
Frequently Asked Questions
Is Amiloxate (Isoamyl p-Methoxycinnamate) safe in cosmetics?
Good safety profile within approved limits. Restricted in EU with 25% maximum concentration; not permitted in the US. The EU classifies Amiloxate (Isoamyl p-Methoxycinnamate) as "restricted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Amiloxate (Isoamyl p-Methoxycinnamate) allowed in the EU?
Amiloxate (Isoamyl p-Methoxycinnamate) EU regulatory status: restricted. Maximum allowed concentration: 25%. This is based on EU Regulation 1223/2009 and its amendments.
What does Amiloxate (Isoamyl p-Methoxycinnamate) do in cosmetics?
Amiloxate (Isoamyl p-Methoxycinnamate) functions as: Antioxidant. It is classified as a UV Filter / Sunscreen in our database. CAS number: 71617-10-2.
What is the Margin of Safety for Amiloxate (Isoamyl p-Methoxycinnamate)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Amiloxate (Isoamyl p-Methoxycinnamate)?
The NOAEL (No Observed Adverse Effect Level) for Amiloxate (Isoamyl p-Methoxycinnamate) is ca.200 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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