Isobutyl Salicylate

INCI: ISOBUTYL SALICYLATE

CAS Number
87-19-4 [^1_15][^1_16]
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA 2213; not in CFR prohibited/restricted lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin sensitizer requiring IFRA compliance for maximum concentration by product category. Acute oral toxicity Cat. 4 (H302) and aquatic hazard (H400/H411) noted; environmental concern for rinse-off products. Not genotoxic or photoirritating.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isobutyl Salicylate safe in cosmetics?

Skin sensitizer requiring IFRA compliance for maximum concentration by product category. Acute oral toxicity Cat. 4 (H302) and aquatic hazard (H400/H411) noted; environmental concern for rinse-off products. Not genotoxic or photoirritating. The EU classifies Isobutyl Salicylate as "permitted". Safety rating: MODERATE.

Is Isobutyl Salicylate allowed in the EU?

Isobutyl Salicylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Salicylate do in cosmetics?

Isobutyl Salicylate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 87-19-4 [^1_15][^1_16].

What is the Margin of Safety for Isobutyl Salicylate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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