Is Isopropyl-Methyloxepanone safe in cosmetics?
Isopropyl-Methyloxepanone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Isopropyl-Methyloxepanone
INCI: ISOPROPYL-METHYLOXEPANONE
Isopropyl-Methyloxepanone (CAS 499-54-7) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 499-54-7 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming agent)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
4-methyl-7-propan-2-yloxepan-2-one
InChIKey
GGAXPLCKKANQED-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - not on FDA prohibited/restricted list
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isopropyl-Methyloxepanone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
237
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
6-HYDROXY-3,7-DIMETHYLOCTANOIC ACID LACTONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/231 (1997)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Isopropyl-Methyloxepanone.
Regulatory Flags
fragrance-component
fda_food_additive
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
6-HYDROXY-3,7-DIMETHYLOCTANOIC ACID LACTONE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Isopropyl-Methyloxepanone allowed in the EU?
Isopropyl-Methyloxepanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropyl-Methyloxepanone do in cosmetics?
Isopropyl-Methyloxepanone functions as: Fragrance (perfuming agent). It is classified as a cosmetic ingredient in our database. CAS number: 499-54-7.
Is Isopropyl-Methyloxepanone used outside cosmetics?
Isopropyl-Methyloxepanone also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isopropyl-Methyloxepanone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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