Good Cosmetic Ingredient NOAEL Data

Lawsonia Inermis Wax

INCI: LAWSONIA INERMIS WAX

CAS Number
84988-66-9
Function
Skin conditioning, emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific restriction for purified wax

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lawsonia Inermis Wax. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 40 mg/kg bw/day oral - - SCCS_PDF_direct

Expert Verdict

Confirm batch lawsone content at or below limit of detection; functionally identical to Lawsonia Inermis Cera in CosIng.

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Concern Level: Low

Frequently Asked Questions

Is Lawsonia Inermis Wax safe in cosmetics?

Confirm batch lawsone content at or below limit of detection; functionally identical to Lawsonia Inermis Cera in CosIng. The EU classifies Lawsonia Inermis Wax as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Lawsonia Inermis Wax allowed in the EU?

Lawsonia Inermis Wax EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lawsonia Inermis Wax do in cosmetics?

Lawsonia Inermis Wax functions as: Skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 84988-66-9.

What is the Margin of Safety for Lawsonia Inermis Wax?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lawsonia Inermis Wax?

The NOAEL (No Observed Adverse Effect Level) for Lawsonia Inermis Wax is 40 mg/kg bw/day based on a toxicological study via oral route in rat. Source: SCCS_PDF_direct.

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