Is Linalyl Propionate safe in cosmetics?
Linalyl Propionate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Linalyl Propionate
Also known as: 3,7-Dimethyl-1,6-octadien-3-ol propanoate, 3,7-Dimethyl-1,6-octadien-3-yl propanoate, EINECS 205-627-5, EINECS 305-130-4, FEMA No. 2645 (+6 more)
INCI: LINALYL PROPIONATE
Linalyl Propionate (CAS 144-39-8) is a cosmetic cosmetic ingredient functioning as Perfuming / Fragrance - floral-type odor with herbal-type flavor; classified as. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Perfuming / Fragrance - floral-type odor with herbal-type flavor; classified as a modern bergamot-lavender note
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
3,7-dimethylocta-1,6-dien-3-yl propanoate
InChIKey
WAQIIHCCEMGYKP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - FEMA number 2645 confirms GRAS status for flavor use; not prohibited or restricted for cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Linalyl Propionate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5184 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
360
Source: WHO/JECFA
JECFA Evaluation
3,7-DIMETHYL-1,6-OCTADIEN-3-YL PROPIONATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/293 (1998)
Source: WHO/JECFA
JECFA Evaluation
LINALYL PROPIONATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/293 (1998)
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Linalyl Propionate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
3,7-Dimethyl-1,6-octadien-3-ol propanoate
3,7-Dimethyl-1,6-octadien-3-yl propanoate
EINECS 205-627-5
EINECS 305-130-4
FEMA No. 2645
Linalool propionate
Linalyl propanoate
NSC 46139
1,6-Octadien-3-ol, 3,7-dimethyl-, propionate
Propionic acid, linalyl ester
UNII-BI845A018T
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186660
Frequently Asked Questions
Is Linalyl Propionate allowed in the EU?
Linalyl Propionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Linalyl Propionate do in cosmetics?
Linalyl Propionate functions as: Perfuming / Fragrance - floral-type odor with herbal-type flavor; classified as a modern bergamot-lavender note. It is classified as a cosmetic ingredient in our database. CAS number: 144-39-8.
Is Linalyl Propionate used outside cosmetics?
Linalyl Propionate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Linalyl Propionate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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