Lobelia Inflata Extract

INCI: LOBELIA INFLATA EXTRACT

CAS Number
84696-23-1
Function
Formerly used as skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes FDA banned OTC lobeline (internal use) in 1993; topical cosmetic use not explicitly prohibited federally but strongly discouraged due to alkaloid toxicity

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU cosmetics under Regulation (EC) 1223/2009 Annex II due to toxic alkaloid (lobeline) content with risk of cardiovascular toxicity, hypotension, and convulsions; avoid in cosmetic formulations.

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Concern Level: High

Regulatory Flags

eu-prohibited toxic-alkaloids avoid eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Lobelia Inflata Extract safe in cosmetics?

Prohibited in EU cosmetics under Regulation (EC) 1223/2009 Annex II due to toxic alkaloid (lobeline) content with risk of cardiovascular toxicity, hypotension, and convulsions; avoid in cosmetic formulations. The EU classifies Lobelia Inflata Extract as "prohibited". Safety rating: POOR.

Is Lobelia Inflata Extract allowed in the EU?

Lobelia Inflata Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Lobelia Inflata Extract do in cosmetics?

Lobelia Inflata Extract functions as: Formerly used as skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-23-1.

What is the Margin of Safety for Lobelia Inflata Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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