Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Magnesium Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=0.043 other | oral | - | oral | REACH |
| NOAEL | >=3124.71 other | oral | - | oral | REACH |
| NOAEL | >=18.23 other | oral | - | oral | REACH |
| NOAEL | >=0.0087 other | oral | - | oral | REACH |
| NOAEL | >=49.88 other | oral | - | oral | REACH |
| NOAEL | >=0.05 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=3600 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=21 other | oral | rat | oral | REACH |
| NOAEL | >=0.01 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=50 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Very low concern. EWG rating of 1 (lowest hazard). Non-toxic, water-soluble salt with no documented sensitization or irritation issues at cosmetic-use concentrations. Magnesium salt of acetic acid; EC No. 205-554-9; highly water-soluble; stable and compatible with strong oxidizing agents should be avoided; synthetic origin
Regulatory Flags
Frequently Asked Questions
Is Magnesium Acetate safe in cosmetics?
Very low concern. EWG rating of 1 (lowest hazard). Non-toxic, water-soluble salt with no documented sensitization or irritation issues at cosmetic-use concentrations. Magnesium salt of acetic acid; EC No. 205-554-9; highly water-soluble; stable and compatible with strong oxidizing agents should be avoided; synthetic origin The EU classifies Magnesium Acetate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Magnesium Acetate allowed in the EU?
Magnesium Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Acetate do in cosmetics?
Magnesium Acetate functions as: Buffering (pH regulator). It is classified as a cosmetic ingredient in our database. CAS number: 142-72-3.
What is the Margin of Safety for Magnesium Acetate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Magnesium Acetate?
The NOAEL (No Observed Adverse Effect Level) for Magnesium Acetate is >=0.043 other based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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