Moderate Cosmetic Ingredient Sensitization Data

Manganese Chloride

INCI: MANGANESE CHLORIDE

CAS Number
7773-01-5
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed in cosmetics; also GRAS as a food-grade nutrient source (21 CFR 184.1446)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Manganese Chloride based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
metal
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: ESSCA 2019/20; NACDG 2021-22

Expert Verdict

Can be irritating at higher concentrations due to chloride ion; potential skin sensitization in susceptible individuals; simple inorganic salt so higher bioavailability than chelated forms. Synthetic origin; highly water-soluble; one of the most basic and commonly available manganese salts; pink crystalline solid

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Concern Level: Moderate

Regulatory Flags

potential-allergen endocrine_disruptor fda_food_additive

Frequently Asked Questions

Is Manganese Chloride safe in cosmetics?

Can be irritating at higher concentrations due to chloride ion; potential skin sensitization in susceptible individuals; simple inorganic salt so higher bioavailability than chelated forms. Synthetic origin; highly water-soluble; one of the most basic and commonly available manganese salts; pink crystalline solid The EU classifies Manganese Chloride as "permitted". Safety rating: MODERATE.

Is Manganese Chloride allowed in the EU?

Manganese Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Manganese Chloride do in cosmetics?

Manganese Chloride functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 7773-01-5.

What is the Margin of Safety for Manganese Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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