Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Myristic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 10000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 20000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Well-established 14-carbon saturated fatty acid that acts as a penetration enhancer; moderately comedogenic, so avoid in acne-prone formulations.
Regulatory Flags
Frequently Asked Questions
Is Myristic Acid safe in cosmetics?
Well-established 14-carbon saturated fatty acid that acts as a penetration enhancer; moderately comedogenic, so avoid in acne-prone formulations. The EU classifies Myristic Acid as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Myristic Acid allowed in the EU?
Myristic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Myristic Acid do in cosmetics?
Myristic Acid functions as: Surfactant, cleansing agent, emulsifier, emollient, opacifier. It is classified as a Cosmetic Ingredient in our database. CAS number: 544-63-8.
What is the Margin of Safety for Myristic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Myristic Acid?
The NOAEL (No Observed Adverse Effect Level) for Myristic Acid is 10000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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