Is N-Methyl-3-Nitro-p-Phenylenediamine safe in cosmetics?
N-Methyl-3-Nitro-p-Phenylenediamine has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
MODERATE
Cosmetic Ingredient
N-Methyl-3-Nitro-p-Phenylenediamine
INCI: N-METHYL-3-NITRO-P-PHENYLENEDIAMINE
N-Methyl-3-Nitro-p-Phenylenediamine (CAS 2973-21-9) is a cosmetic cosmetic ingredient functioning as Semi-permanent (direct) hair dye. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
Function
Semi-permanent (direct) hair dye
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
4-N-methyl-2-nitrobenzene-1,4-diamine
InChIKey
XSHZMHVULBOPDY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted under coal tar hair dye exemption (21 USC §361(a)); caution statement required per 21 CFR 740.2
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for N-Methyl-3-Nitro-p-Phenylenediamine.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1284
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1284
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Editorial summary
Preliminary editorial summary for N-Methyl-3-Nitro-p-Phenylenediamine — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is N-Methyl-3-Nitro-p-Phenylenediamine allowed in the EU?
N-Methyl-3-Nitro-p-Phenylenediamine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does N-Methyl-3-Nitro-p-Phenylenediamine do in cosmetics?
N-Methyl-3-Nitro-p-Phenylenediamine functions as: Semi-permanent (direct) hair dye. It is classified as a cosmetic ingredient in our database. CAS number: 2973-21-9.
Compliance Tools
Check N-Methyl-3-Nitro-p-Phenylenediamine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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