Is Neopentyl Glycol Diisostearate safe in cosmetics?
Neopentyl Glycol Diisostearate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Neopentyl Glycol Diisostearate
INCI: NEOPENTYL GLYCOL DIISOSTEARATE
Neopentyl Glycol Diisostearate (CAS 68855-18-5) is a cosmetic cosmetic ingredient functioning as Skin conditioning, emollient, viscosity controlling. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68855-18-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, emollient, viscosity controlling
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,2-dimethylpropane-1,3-diol;heptanoic acid
InChIKey
VRYUGRNJSPQWJC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR reviewed under branched-chain esters; safe in present practices
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Neopentyl Glycol Diisostearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Neopentyl Glycol Diisostearate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Neopentyl Glycol Diisostearate.
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Neopentyl Glycol Diisostearate allowed in the EU?
Neopentyl Glycol Diisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Neopentyl Glycol Diisostearate do in cosmetics?
Neopentyl Glycol Diisostearate functions as: Skin conditioning, emollient, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 68855-18-5.
Is Neopentyl Glycol Diisostearate used outside cosmetics?
Neopentyl Glycol Diisostearate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Neopentyl Glycol Diisostearate compliance across multiple jurisdictions:
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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