Neopentyl Glycol Diisostearate
INCI: NEOPENTYL GLYCOL DIISOSTEARATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Neopentyl Glycol Diisostearate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1613 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 1613 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Minimal concerns; standard product safety assessment sufficient
Frequently Asked Questions
Is Neopentyl Glycol Diisostearate safe in cosmetics?
Minimal concerns; standard product safety assessment sufficient The EU classifies Neopentyl Glycol Diisostearate as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Neopentyl Glycol Diisostearate allowed in the EU?
Neopentyl Glycol Diisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Neopentyl Glycol Diisostearate do in cosmetics?
Neopentyl Glycol Diisostearate functions as: Skin conditioning, emollient, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 68855-18-5.
What is the Margin of Safety for Neopentyl Glycol Diisostearate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Neopentyl Glycol Diisostearate?
The NOAEL (No Observed Adverse Effect Level) for Neopentyl Glycol Diisostearate is 1613 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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