Is NEROLIDOL ISOMERS safe in cosmetics?
NEROLIDOL ISOMERS has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
NEROLIDOL ISOMERS
Also known as: 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene, 3-01-00-02042, BRN 1724135, EINECS 230-597-5, FEMA No. 2772 (+3 more)
NEROLIDOL ISOMERS (CAS 7212-44-4) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 7212-44-4 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol
InChIKey
FQTLCLSUCSAZDY-SDNWHVSQSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
EPA ToxValDB — Toxicity Values
4 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LOEL | =500 mg/kg-day | House Mouse | oral | acute | ECOTOX |
| LD50 | =15000 mg/kg | Mouse | oral | - | ChemIDplus |
| LD50 | >5000 mg/kg | Rabbit | dermal | - | ChemIDplus |
| LD50 | >5000 mg/kg | Rat | oral | - | ChemIDplus |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Regulatory (3)
JECFA Number
1646
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
3,7,11-TRIMETHYL-1,6,10-DODECATRIEN-3-OL | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
NEROLIDOL | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NEROLIDOL ISOMERS.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
Known Synonyms
3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene
3-01-00-02042
BRN 1724135
EINECS 230-597-5
FEMA No. 2772
Methylvinylhomogeranyl carbinol
EPA Pesticide Chemical Code 128910
UNII-QR6IP857S6
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
active_ingredient; Europe; Pesticides
pharmaceutical
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is NEROLIDOL ISOMERS allowed in the EU?
NEROLIDOL ISOMERS EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NEROLIDOL ISOMERS do in cosmetics?
NEROLIDOL ISOMERS functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 7212-44-4.
Is NEROLIDOL ISOMERS used outside cosmetics?
NEROLIDOL ISOMERS also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NEROLIDOL ISOMERS compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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