Is Potassium Azeloyl Diglycinate safe in cosmetics?
Potassium Azeloyl Diglycinate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Potassium Azeloyl Diglycinate
Also known as: UNII-N02RVN6NYP, Azeloglicina, Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, monopotassium salt, Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, potassium salt (1:1)
INCI: POTASSIUM AZELOYL DIGLYCINATE
Potassium Azeloyl Diglycinate (CAS 477773-67-4) is a cosmetic cosmetic ingredient functioning as Skin brightening, anti-inflammatory, sebum normalizing, skin conditioning,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 477773-67-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin brightening, anti-inflammatory, sebum normalizing, skin conditioning, anti-acne
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
potassium 2-[[9-(carboxymethylamino)-9-oxononanoyl]amino]acetate
InChIKey
HOZMBDKPRFLCKN-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Parent compound azelaic acid (15-20%) is prescription drug. PAD is unregulated as cosmetic ingredient.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Potassium Azeloyl Diglycinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Potassium Azeloyl Diglycinate, relevant to systemic exposure and MoS calculations.
Absorption %
4-8%
Penetration Level
stratum-corneum
Penetration Depth
stratum corneum/epidermis
Molecular Weight
360.4 Da
Log P
-2.1
Systemic Absorption
minimal
Topical Bioavailability
2-6%
Safety Margin Factor
low
Vehicle Dependent
Yes — absorption varies by formulation
Source: Cosmetic Science
Additional Ingredient Properties
1 property record from structured ingredient metadata.
dermal_absorption
{"molecular_weight_da": "360.4", "log_p_value": "-2.1", "skin_penetration_level": "stratum-corneum", "penetration_depth": "stratum corneum/epidermis", "absorption_pct": "4-8", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "yes", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "2-6", "safety_margin_factor": "low", "so…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Potassium Azeloyl Diglycinate.
Known Synonyms
UNII-N02RVN6NYP
Azeloglicina
Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, monopotassium salt
Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, potassium salt (1:1)
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Potassium Azeloyl Diglycinate allowed in the EU?
Potassium Azeloyl Diglycinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Azeloyl Diglycinate do in cosmetics?
Potassium Azeloyl Diglycinate functions as: Skin brightening, anti-inflammatory, sebum normalizing, skin conditioning, anti-acne. It is classified as a cosmetic ingredient in our database. CAS number: 477773-67-4.
Is Potassium Azeloyl Diglycinate used outside cosmetics?
Potassium Azeloyl Diglycinate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Potassium Azeloyl Diglycinate compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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