Is Azeloglicina (PAD) safe in cosmetics?
Azeloglicina (PAD) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Azeloglicina (PAD)
Also known as: UNII-N02RVN6NYP, Azeloglicina, Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, monopotassium salt, Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, potassium salt (1:1)
INCI: POTASSIUM AZELOYL DIGLYCINATE
Azeloglicina (PAD) (CAS 477773-67-4) is a cosmetic active ingredient functioning as anti-aging. EU Regulation 1223/2009 status: permitted, max 12.7%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 477773-67-4 →
Auto-generated CPSR Part A draft with source citations
Function
anti-aging
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
potassium 2-[[9-(carboxymethylamino)-9-oxononanoyl]amino]acetate
InChIKey
HOZMBDKPRFLCKN-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
EU Max Conc.
12.7%
US US Status
permitted
US Notes
CIR Expert Panel concluded dicarboxylic acids (including azelaic acid salts and esters) are safe in present practices of use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Azeloglicina (PAD).
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Azeloglicina (PAD), relevant to systemic exposure and MoS calculations.
Absorption %
4-8%
Penetration Level
stratum-corneum
Penetration Depth
stratum corneum/epidermis
Molecular Weight
360.4 Da
Log P
-2.1
Systemic Absorption
minimal
Topical Bioavailability
2-6%
Safety Margin Factor
low
Vehicle Dependent
Yes — absorption varies by formulation
Source: Cosmetic Science
Additional Ingredient Properties
1 property record from structured ingredient metadata.
dermal_absorption
{"molecular_weight_da": "360.4", "log_p_value": "-2.1", "skin_penetration_level": "stratum-corneum", "penetration_depth": "stratum corneum/epidermis", "absorption_pct": "4-8", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "yes", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "2-6", "safety_margin_factor": "low", "so…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Azeloglicina (PAD).
Known Synonyms
UNII-N02RVN6NYP
Azeloglicina
Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, monopotassium salt
Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-, potassium salt (1:1)
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Azeloglicina (PAD) allowed in the EU?
Azeloglicina (PAD) EU regulatory status: permitted. Maximum allowed concentration: 12.7%. This is based on EU Regulation 1223/2009 and its amendments.
What does Azeloglicina (PAD) do in cosmetics?
Azeloglicina (PAD) functions as: anti-aging. It is classified as a Active Ingredient in our database. CAS number: 477773-67-4.
Is Azeloglicina (PAD) used outside cosmetics?
Azeloglicina (PAD) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Azeloglicina (PAD) compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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