Is Potassium Bromate safe in cosmetics?
Potassium Bromate has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Potassium Bromate
Also known as: Bromate, potassium, EEC No. E924, EINECS 231-829-8, NSC 215200, Potassium bromate(DOT) (+3 more)
INCI: POTASSIUM BROMATE
Potassium Bromate (CAS 7758-01-2) is a cosmetic cosmetic ingredient functioning as Oxidizing agent historically used in permanent wave neutralizers. NOAEL 20 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7758-01-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Potassium Bromate is prohibited in EU cosmetics but has active industrial GHS classifications (H271, H301, H350, H272, H302, H320, H335, H341).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Oxidizing agent historically used in permanent wave neutralizers
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
potassium bromate
InChIKey
OCATYIAKPYKMPG-UHFFFAOYSA-M
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not explicitly banned in cosmetics but classified as a probable carcinogen; banned in food in many jurisdictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Potassium Bromate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Ingestion could cause effects on the kidneys and central nervous system. This may result in renal failure, respiratory depression and hearing loss. The effects may be delayed.
Long-term Exposure Effects
This substance is possibly carcinogenic to humans.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Potassium Bromate across SCCS product categories, with measured dermal absorption where available.
IARC Carcinogenicity
International Agency for Research on Cancer (WHO) monograph evaluation.
IARC Group
2B
Volume
Sup 7, 73
Evaluation Year
1998
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
OxidiserHealth HazardAcute Toxicity
Hazard Class and Category
Ox. Sol. 1; Carc. 1B; Acute Tox. 3 *
Hazard Statements
- H271 May cause fire or explosion; strong oxidiser
- H350 May cause cancer
- H301 Toxic if swallowed
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 461
(EC) 2009/1223
CMR: Carcinogenic Cat. 1B()
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 461
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (5)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | banned | - | all cosmetics |
| CA | banned | - | - |
| CA | restricted | Child-resistant packaging required if ≥50 mg | Legacy restriction — now effectively prohibited |
| CA | restricted | See conditions | Legacy hair waving products with specific labelling |
| ASEAN | banned | - | All cosmetic products prohibited |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (5)
Carcinogen Classification
2B, possibly carcinogenic to humans. (L135)
Source: Toxin and Toxin Target Database (T3DB)
Carcinogen Classification
Potassium bromate | Group 2B: Possibly carcinogenic to humans | Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print) | Volume 73: (1999) Some Chemicals that Cause Tumours of the Kidney or Urinary Bladder in Rodents and Some Other Substances
Source: International Agency for Research on Cancer (IARC)
Evidence for Carcinogenicity
Evaluation: There is inadequate evidence in humans for the carcinogenicity of potassium bromate. There is sufficient evidence in experimental animals for the carcinogenicity of potassium bromate. Overall evaluation: Potassium bromate is possibly carcinogenic to humans (Group 2B). | Under the current Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986), bromate would be classified as B2, prob
Source: Hazardous Substances Data Bank (HSDB)
ICSC Safety Card
1115
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
An irritant to skin, eyes, and mucous membranes.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (1)
JECFA Evaluation
POTASSIUM BROMATE | 1995 | At its forty-fourth meeting (1995), in light of new data showing residual levels of bromate in bread, the Committee considered that the conclusions of the thirty-ninth meeting (1992) still applied. | TRS 859-JECFA 44/35 | FAS 30-JECFA 39/285 (1992)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Filler
Food preservative
Leavening agent
Oxidizing agent
Regulatory List Membership (4)
California Proposition 65 (OEHHA)
EU Banned in Cosmetics
FDA Substances Added to Food (EAFUS)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Potassium Bromate.
Regulatory Flags
prop65
eu_banned_cosmetics
fda_food_additive
eu_cosing_listed
Known Synonyms
Bromate, potassium
EEC No. E924
EINECS 231-829-8
NSC 215200
Potassium bromate(DOT)
UNII-04MB35W6ZA
E924
potassium trioxobromate
Chemical Function
Oxidizing agent
Leavening agent
Filler
Food preservative
Regulatory Lists
OEHHA Proposition 65 (3/2019)
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
banned; Europe; Personal care
OEHHA Proposition 65 (1/2023)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
POTASSIUM BROMATE
ChEMBL ID
CHEMBL2311074
Frequently Asked Questions
Is Potassium Bromate allowed in the EU?
Potassium Bromate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Bromate do in cosmetics?
Potassium Bromate functions as: Oxidizing agent historically used in permanent wave neutralizers. It is classified as a cosmetic ingredient in our database. CAS number: 7758-01-2.
Is Potassium Bromate used outside cosmetics?
Potassium Bromate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Potassium Bromate have different safety status in cosmetics vs industrial chemicals?
Potassium Bromate is prohibited in EU cosmetics but has active industrial GHS classifications (H271, H301, H350, H272, H302, H320, H335, H341).
Compliance Tools
Check Potassium Bromate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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