Excellent Cosmetic Ingredient NOAEL Data

Propylene Glycol Alginate

INCI: PROPYLENE GLYCOL ALGINATE

CAS Number
9005-37-2
Function
Binding, Viscosity controlling
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; GRAS as food additive (21 CFR 172.858)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Propylene Glycol Alginate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 7500 mg/kg bw/day oral mouse Chronic COSMOS_DB
NOAEL 2500 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 2000 mg/kg bw/day oral guinea pig Chronic COSMOS_DB
NOAEL 2500 mg/kg bw/day oral cat Subchronic COSMOS_DB
NOAEL 3750 mg/kg bw/day oral dog Chronic COSMOS_DB
NOAEL 780 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 720 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 700 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 800 mg/kg bw/day oral rabbit Developmental COSMOS_DB
dose_tested 7500 mg/kg bw/day oral mouse Chronic COSMOS_DB

Expert Verdict

Seaweed-derived โ€“ verify supplier COA for heavy metal traces (arsenic, lead, cadmium); pH-sensitive viscosity behavior; film-forming properties may affect formulation stability

โš ๏ธ
Concern Level: None

Regulatory Flags

ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Propylene Glycol Alginate safe in cosmetics?

Seaweed-derived โ€“ verify supplier COA for heavy metal traces (arsenic, lead, cadmium); pH-sensitive viscosity behavior; film-forming properties may affect formulation stability The EU classifies Propylene Glycol Alginate as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Propylene Glycol Alginate allowed in the EU?

Propylene Glycol Alginate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Alginate do in cosmetics?

Propylene Glycol Alginate functions as: Binding, Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9005-37-2.

What is the Margin of Safety for Propylene Glycol Alginate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Propylene Glycol Alginate?

The NOAEL (No Observed Adverse Effect Level) for Propylene Glycol Alginate is 7500 mg/kg bw/day based on a Chronic study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Propylene Glycol Alginate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Propylene Glycol Alginate in your formulation.