Regulatory Status
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Safety Data
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Expert Verdict
Chronic high-dose oral pyridoxine (>200 mg/day) is associated with peripheral neuropathy; no relevance at cosmetic topical levels. pH-sensitive — formulate at pH 3–5 for optimal stability [^1_8]
Frequently Asked Questions
Is Pyridoxine HCl safe in cosmetics?
Chronic high-dose oral pyridoxine (>200 mg/day) is associated with peripheral neuropathy; no relevance at cosmetic topical levels. pH-sensitive — formulate at pH 3–5 for optimal stability [^1_8] The EU classifies Pyridoxine HCl as "permitted". Safety rating: EXCELLENT.
Is Pyridoxine HCl allowed in the EU?
Pyridoxine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pyridoxine HCl do in cosmetics?
Pyridoxine HCl functions as: Skin conditioning, hair conditioning, antistatic [^1_9]. It is classified as a cosmetic ingredient in our database. CAS number: 58-56-0 [^1_8].
What is the Margin of Safety for Pyridoxine HCl?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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