Ribose

INCI: RIBOSE [^1_8]

CAS Number
50-69-1 [^1_8]
Function
Humectant, skin conditioning (fundamental ATP building block — stimulates cellular energy metabolism) [^1_9]
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; also GRAS as dietary supplement — no FDA cosmetic restrictions [^1_8]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

May undergo Maillard browning with amines at elevated temperatures — verify compatibility in amino acid-containing formulations; hygroscopic, so proper packaging required [^1_9]

⚠️
Concern Level: None

Frequently Asked Questions

Is Ribose safe in cosmetics?

May undergo Maillard browning with amines at elevated temperatures — verify compatibility in amino acid-containing formulations; hygroscopic, so proper packaging required [^1_9] The EU classifies Ribose as "permitted". Safety rating: EXCELLENT.

Is Ribose allowed in the EU?

Ribose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ribose do in cosmetics?

Ribose functions as: Humectant, skin conditioning (fundamental ATP building block — stimulates cellular energy metabolism) [^1_9]. It is classified as a cosmetic ingredient in our database. CAS number: 50-69-1 [^1_8].

What is the Margin of Safety for Ribose?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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