Good Cosmetic Ingredient

Royal Jelly Extract

INCI: ROYAL JELLY EXTRACT

CAS Number
8031-67-2
Function
Skin conditioning; 10-HDA, royalactin
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not prohibited by FDA. No CIR safety assessment. FTC and FDA have challenged anti-aging claims as unsubstantiated. Safe for general population at typical concentrations (0.1-0.5%); contraindicated for individuals with bee venom allergy, atopic dermatitis, asthma, or dust mite allergy.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU: Listed in EU Cosmetic Ingredient Inventory with no restrictions; permitted for skin conditioning use. US: Not prohibited by FDA; no CIR assessment published. High-molecular-weight proteins limit dermal absorption to surface-level conditioning. Moderate sensitization risk documented in atopic populations and those with bee-related allergies.

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Concern Level: Moderate

Regulatory Flags

bee-derived allergen-risk-atopic no-cir-review anaphylaxis-reported not-vegan efficacy-claims-disputed

Frequently Asked Questions

Is Royal Jelly Extract safe in cosmetics?

EU: Listed in EU Cosmetic Ingredient Inventory with no restrictions; permitted for skin conditioning use. US: Not prohibited by FDA; no CIR assessment published. High-molecular-weight proteins limit dermal absorption to surface-level conditioning. Moderate sensitization risk documented in atopic populations and those with bee-related allergies. The EU classifies Royal Jelly Extract as "permitted". Safety rating: GOOD.

Is Royal Jelly Extract allowed in the EU?

Royal Jelly Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Royal Jelly Extract do in cosmetics?

Royal Jelly Extract functions as: Skin conditioning; 10-HDA, royalactin. It is classified as a Cosmetic Ingredient in our database. CAS number: 8031-67-2.

What is the Margin of Safety for Royal Jelly Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Royal Jelly Extract compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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