Rubia Tinctorum Root

INCI: RUBIA TINCTORUM ROOT

CAS Number
84650-16-8 (whole root)
Function
Colorant, Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not approved as color additive; not specifically restricted for cosmetic use but carries significant safety burden

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿšจ CRITICAL: Lucidin is mutagenic in Salmonella strains ยฑS9 activation, mutagenic at HGPRT locus in V79 cells, induces DNA single-strand breaks, DNA-protein cross-links, and DNA repair synthesis; rubiadin is also highly genotoxic; carcinogenic in rat kidney and liver

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Concern Level: High

Regulatory Flags

colorant

Frequently Asked Questions

Is Rubia Tinctorum Root safe in cosmetics?

๐Ÿšจ CRITICAL: Lucidin is mutagenic in Salmonella strains ยฑS9 activation, mutagenic at HGPRT locus in V79 cells, induces DNA single-strand breaks, DNA-protein cross-links, and DNA repair synthesis; rubiadin is also highly genotoxic; carcinogenic in rat kidney and liver The EU classifies Rubia Tinctorum Root as "permitted". Safety rating: POOR.

Is Rubia Tinctorum Root allowed in the EU?

Rubia Tinctorum Root EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rubia Tinctorum Root do in cosmetics?

Rubia Tinctorum Root functions as: Colorant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84650-16-8 (whole root).

What is the Margin of Safety for Rubia Tinctorum Root?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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