Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Salicylaldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 300 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 10 mg/kg bw/day | oral | rat | oral | REACH |
Sensitization Profile
Contact sensitization data for Salicylaldehyde based on clinical patch test studies and IFRA standards.
Source: EU 2023/1545; SCCS/1459/11
Expert Verdict
Fragrance allergen requiring mandatory EU labeling; skin/eye irritant potential; not recommended for sensitive skin formulations without careful dose control
Regulatory Flags
Frequently Asked Questions
Is Salicylaldehyde safe in cosmetics?
Fragrance allergen requiring mandatory EU labeling; skin/eye irritant potential; not recommended for sensitive skin formulations without careful dose control The EU classifies Salicylaldehyde as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Salicylaldehyde allowed in the EU?
Salicylaldehyde EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Salicylaldehyde do in cosmetics?
Salicylaldehyde functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 90-02-8.
What is the Margin of Safety for Salicylaldehyde?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Salicylaldehyde?
The NOAEL (No Observed Adverse Effect Level) for Salicylaldehyde is 500 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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