sh-Polypeptide-123

INCI: SH-POLYPEPTIDE-123

CAS Number
1375784-79-4
Function
Skin protecting; highly purified type III human-like collagen (collagen alpha-1(III) chain, up to 1466 amino acids)
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted cosmetic ingredient; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

May contain disulfide bonds and/or glycosylation; no adverse safety signals reported

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Concern Level: None

Frequently Asked Questions

Is sh-Polypeptide-123 safe in cosmetics?

May contain disulfide bonds and/or glycosylation; no adverse safety signals reported The EU classifies sh-Polypeptide-123 as "permitted". Safety rating: EXCELLENT.

Is sh-Polypeptide-123 allowed in the EU?

sh-Polypeptide-123 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Polypeptide-123 do in cosmetics?

sh-Polypeptide-123 functions as: Skin protecting; highly purified type III human-like collagen (collagen alpha-1(III) chain, up to 1466 amino acids). It is classified as a cosmetic ingredient in our database. CAS number: 1375784-79-4.

What is the Margin of Safety for sh-Polypeptide-123?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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