Is sh-Polypeptide-123 safe in cosmetics?
sh-Polypeptide-123 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
sh-Polypeptide-123
INCI: SH-POLYPEPTIDE-123
sh-Polypeptide-123 (CAS 1375784-79-4) is a cosmetic cosmetic ingredient functioning as Skin protecting; highly purified type III human-like collagen (collagen. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1375784-79-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin protecting; highly purified type III human-like collagen (collagen alpha-1(III) chain, up to 1466 amino acids)
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted cosmetic ingredient; no specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for sh-Polypeptide-123.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for sh-Polypeptide-123.
Chemical Function
Humectant
Frequently Asked Questions
Is sh-Polypeptide-123 allowed in the EU?
sh-Polypeptide-123 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does sh-Polypeptide-123 do in cosmetics?
sh-Polypeptide-123 functions as: Skin protecting; highly purified type III human-like collagen (collagen alpha-1(III) chain, up to 1466 amino acids). It is classified as a cosmetic ingredient in our database. CAS number: 1375784-79-4.
Compliance Tools
Check sh-Polypeptide-123 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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