Silybum Marianum Seed Extract

INCI: SILYBUM MARIANUM SEED EXTRACT

CAS Number
84604-20-6
Function
Skin Conditioning, Antioxidant
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; well-documented dietary supplement history supports safety profile

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Most data-rich of the Silybum derivatives; Asteraceae cross-reactivity remains a theoretical flag. Verify solvent residues if obtained via solvent extraction

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Concern Level: None

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Silybum Marianum Seed Extract safe in cosmetics?

Most data-rich of the Silybum derivatives; Asteraceae cross-reactivity remains a theoretical flag. Verify solvent residues if obtained via solvent extraction The EU classifies Silybum Marianum Seed Extract as "permitted". Safety rating: EXCELLENT.

Is Silybum Marianum Seed Extract allowed in the EU?

Silybum Marianum Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Silybum Marianum Seed Extract do in cosmetics?

Silybum Marianum Seed Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84604-20-6.

What is the Margin of Safety for Silybum Marianum Seed Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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