Is Sodium Bromate safe in cosmetics?
Sodium Bromate has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
Sodium Bromate
Also known as: Dyetone, EINECS 232-160-4, Neutralizer K-126, Neutralizer K-140, Neutralizer K-938 (+4 more)
INCI: SODIUM BROMATE
Sodium Bromate (CAS 7789-38-0) is a cosmetic cosmetic ingredient functioning as Oxidizing agent (historically used in hair permanent wave neutralizers). NOAEL 21 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited; GHS signal word DANGER. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7789-38-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Sodium Bromate is prohibited in EU cosmetics but has active industrial GHS classifications (H271, H272, H301, H302, H315, H319, H335, H341).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Oxidizing agent (historically used in hair permanent wave neutralizers)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
sodium bromate
InChIKey
XUXNAKZDHHEHPC-UHFFFAOYSA-M
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Restricted; FDA has issued warnings; classified as potential carcinogen (Group 2B by IARC); not commonly used in modern formulations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Bromate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
DANGER
Pictograms
Flam circleCancerHealth haz
Hazard Statements
May cause fire or explosion; strong oxidizer Causes damage to kidneys and nervous system if swallowed
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Ingestion could cause effects on the kidneys and nervous system. This may result in renal failure, respiratory depression, hearing loss and peripheral neuropathy. The effects may be delayed.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Sodium Bromate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | restricted | 10.5 | Neutralizers for hair waving |
| CA | restricted | Child-resistant if ≥600 mg | Legacy restriction |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (5)
Carcinogen Classification
Potassium bromate: 2B, possibly carcinogenic to humans. (L135)
Source: Toxin and Toxin Target Database (T3DB)
Evidence for Carcinogenicity
Under the current Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986), bromate would be classified as B2, probable human carcinogen. Under the Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996), bromate should be evaluated as a likely human carcinogen by the oral route of exposure. Insufficient data are available to evaluate the human carcinogenic potential of bromate by th
Source: Hazardous Substances Data Bank (HSDB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
ICSC Safety Card
0196
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
The substance is irritating to the eyes, skin and respiratory tract.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Oxidizing agent
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Bromate.
Regulatory Flags
endocrine_disruptor
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Sodium Bromate by CAS number or substance name.
Studies
6
Lowest NOAEL
7.7 mg/kg bw/day
Highest NOAEL
256 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Dyetone
EINECS 232-160-4
Neutralizer K-126
Neutralizer K-140
Neutralizer K-938
NSC 77383
Sodium bromate(DOT)
UNII-U54JK6453O
NaBrO3
Chemical Function
Oxidizing agent
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1348453
Frequently Asked Questions
Is Sodium Bromate allowed in the EU?
Sodium Bromate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Bromate do in cosmetics?
Sodium Bromate functions as: Oxidizing agent (historically used in hair permanent wave neutralizers). It is classified as a cosmetic ingredient in our database. CAS number: 7789-38-0.
Is Sodium Bromate classified as hazardous under GHS?
Sodium Bromate carries a GHS signal word of "DANGER". Hazard statements: May cause fire or explosion; strong oxidizer Causes damage to kidneys and nervous system if swallowed. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is Sodium Bromate used outside cosmetics?
Sodium Bromate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Sodium Bromate have different safety status in cosmetics vs industrial chemicals?
Sodium Bromate is prohibited in EU cosmetics but has active industrial GHS classifications (H271, H272, H301, H302, H315, H319, H335, H341).
Compliance Tools
Check Sodium Bromate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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