Poor Cosmetic Ingredient NOAEL Data GHS Classified

Sodium Bromate

INCI: SODIUM BROMATE

CAS Number
7789-38-0
Function
Oxidizing agent (historically used in hair permanent wave neutralizers)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Restricted; FDA has issued warnings; classified as potential carcinogen (Group 2B by IARC); not commonly used in modern formulations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Sodium Bromate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 63 mg/kg bw/day oral - oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
flam circle; cancer;health haz
Hazard Statements
May cause fire or explosion; strong oxidizer Causes damage to kidneys and nervous system if swallowed
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Ingestion could cause effects on the kidneys and nervous system. This may result in renal failure, respiratory depression, hearing loss and peripheral neuropathy. The effects may be delayed.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Expert Verdict

PROHIBITED in EU. IARC Group 2B carcinogen; causes nephrotoxicity, ototoxicity; historically linked to hearing loss in occupational exposure. Do not formulate

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Concern Level: High

Regulatory Flags

endocrine_disruptor

Frequently Asked Questions

Is Sodium Bromate safe in cosmetics?

PROHIBITED in EU. IARC Group 2B carcinogen; causes nephrotoxicity, ototoxicity; historically linked to hearing loss in occupational exposure. Do not formulate The EU classifies Sodium Bromate as "prohibited". Safety rating: POOR. 1 toxicological study endpoint(s) are available in our database.

Is Sodium Bromate allowed in the EU?

Sodium Bromate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Bromate do in cosmetics?

Sodium Bromate functions as: Oxidizing agent (historically used in hair permanent wave neutralizers). It is classified as a cosmetic ingredient in our database. CAS number: 7789-38-0.

What is the Margin of Safety for Sodium Bromate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Bromate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Bromate is 63 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

Is Sodium Bromate classified as hazardous under GHS?

Sodium Bromate carries a GHS signal word of "DANGER". Hazard statements: May cause fire or explosion; strong oxidizer Causes damage to kidneys and nervous system if swallowed. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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