Sodium Fumarate

Also known as: 2-​Butenedioic acid (2E)​-​, sodium salt (1:2), 2-Butenedioic acid (2E)-, disodium salt, 2-Butenedioic acid (E)-, disodium salt, Fumarate de disodium, disodium fumarate (+9 more)

INCI: SODIUM FUMARATE

Sodium Fumarate (CAS 17013-01-3) is a cosmetic cosmetic ingredient functioning as Skin conditioning, buffering agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 17013-01-3 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, buffering agent
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C4H2Na2O4
MW
160.04 g/mol
PubChem CID
6364607
IUPAC Name
disodium;(E)-but-2-enedioate
InChIKey
MSJMDZAOKORVFC-SEPHDYHBSA-L

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted; fumaric acid and its salts are GRAS for food — no specific cosmetic restrictions

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Fumarate.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
pH regulating agent

Expert Verdict

Expert safety assessment and concern-level summary for Sodium Fumarate.

Regulatory Flags

potential-allergen fda_food_additive jecfa_safe

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Sodium Fumarate by CAS number or substance name.

Studies
4
Lowest NOAEL
500 mg/kg
Highest NOAEL
500 mg/kg
CIR_vision_codex

Known Synonyms

2-​Butenedioic acid (2E)​-​, sodium salt (1:2) 2-Butenedioic acid (2E)-, disodium salt 2-Butenedioic acid (E)-, disodium salt Fumarate de disodium disodium fumarate Dinatriumfumarat fumarato de disodio Fumaric acid disodium salt FUMARATE, DISODIUM EINECS 241-087-7 Fumaran sodny UNII-0578QTK490 E365 Fumaric acid, disodium salt

Chemical Function

pH regulating agent

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
49
View full pharmaceutical profile →

Frequently Asked Questions

Is Sodium Fumarate safe in cosmetics?

Sodium Fumarate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Sodium Fumarate allowed in the EU?

Sodium Fumarate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Fumarate do in cosmetics?

Sodium Fumarate functions as: Skin conditioning, buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: 17013-01-3.

Is Sodium Fumarate used outside cosmetics?

Sodium Fumarate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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Disodium Fumarate
Good Chemical family
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