Sodium Oxymethylene Sulfoxylate
INCI: SODIUM OXYMETHYLENE SULFOXYLATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Sodium Oxymethylene Sulfoxylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 600 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Strong reducing agent (also known as Rongalite); releases formaldehyde under certain conditions (heat, acid); formaldehyde is a known sensitizer and carcinogen – must verify no free formaldehyde release in final product
Regulatory Flags
Frequently Asked Questions
Is Sodium Oxymethylene Sulfoxylate safe in cosmetics?
Strong reducing agent (also known as Rongalite); releases formaldehyde under certain conditions (heat, acid); formaldehyde is a known sensitizer and carcinogen – must verify no free formaldehyde release in final product The EU classifies Sodium Oxymethylene Sulfoxylate as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Sodium Oxymethylene Sulfoxylate allowed in the EU?
Sodium Oxymethylene Sulfoxylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Oxymethylene Sulfoxylate do in cosmetics?
Sodium Oxymethylene Sulfoxylate functions as: Reducing agent – changes chemical nature by adding hydrogen or removing oxygen. It is classified as a cosmetic ingredient in our database. CAS number: 149-44-0.
What is the Margin of Safety for Sodium Oxymethylene Sulfoxylate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Oxymethylene Sulfoxylate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Oxymethylene Sulfoxylate is 600 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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