Excellent Cosmetic Ingredient NOAEL Data

Sterculia Urens Gum

INCI: STERCULIA URENS GUM

CAS Number
9000-36-6
Function
Binding, Emulsion Stabilising, Hair Fixing, Viscosity Controlling, Masking
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS (Generally Recognized as Safe) as Karaya Gum for food use; permitted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Sterculia Urens Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 800 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
NOAEL 3000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
NOAEL 5000 mg/kg bw/day oral dog Short Term Toxicity COSMOS_DB
NOAEL 170 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 300 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 600 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 7000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

โœ… Minimal concerns. Ensure gum is properly purified to avoid microbial contamination (standard for natural gums). E416 food-grade classification supports safety

โš ๏ธ
Concern Level: None

Regulatory Flags

natural-origin fda_food_additive

Frequently Asked Questions

Is Sterculia Urens Gum safe in cosmetics?

โœ… Minimal concerns. Ensure gum is properly purified to avoid microbial contamination (standard for natural gums). E416 food-grade classification supports safety The EU classifies Sterculia Urens Gum as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Sterculia Urens Gum allowed in the EU?

Sterculia Urens Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sterculia Urens Gum do in cosmetics?

Sterculia Urens Gum functions as: Binding, Emulsion Stabilising, Hair Fixing, Viscosity Controlling, Masking. It is classified as a cosmetic ingredient in our database. CAS number: 9000-36-6.

What is the Margin of Safety for Sterculia Urens Gum?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sterculia Urens Gum?

The NOAEL (No Observed Adverse Effect Level) for Sterculia Urens Gum is 800 mg/kg bw/day based on a Developmental study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.

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