Is Tetradecane safe in cosmetics?
Tetradecane has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted.
Moderate
Cosmetic Ingredient
Tetradecane
Also known as: 4-01-00-00520, BRN 1733859, EINECS 211-096-0, UNII-03LY784Y58
INCI: TETRADECANE
Tetradecane (CAS 629-59-4) is a cosmetic cosmetic ingredient functioning as Perfuming, solvent, emollient. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 629-59-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Tetradecane is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Perfuming, solvent, emollient
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
tetradecane
InChIKey
BGHCVCJVXZWKCC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not specifically restricted; used in cosmetics under general provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetradecane.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Tetradecane across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Vapor or mist is irritating to the eyes, mucous membranes, and upper respiratory tract. It causes skin irritation.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Solvent
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Tetradecane.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
4-01-00-00520
BRN 1733859
EINECS 211-096-0
UNII-03LY784Y58
Chemical Function
Fragrance
Solvent
Flavouring and nutrient
Regulatory Lists
detected; Other direct contact consumer goods; Other indirect contact consumer goods
air; detected; emissions; Europe; Vehicle - car interior
detected; Europe; Vehicle - car interior
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
IFRA Transparency
Europe
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TETRADECANE
ChEMBL ID
CHEMBL135488
Frequently Asked Questions
Is Tetradecane allowed in the EU?
Tetradecane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetradecane do in cosmetics?
Tetradecane functions as: Perfuming, solvent, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 629-59-4.
Is Tetradecane used outside cosmetics?
Tetradecane also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Tetradecane have different safety status in cosmetics vs industrial chemicals?
Tetradecane is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Tetradecane compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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