Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Tetradecane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1800 2285 | 1995 | rat | inhalation | REACH |
| NOAEL | >=1800 2285 | inhalation | - | inhalation | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=900 ppm | 1995 | rat | inhalation | REACH |
| NOAEL | >=900 ppm | inhalation | - | inhalation | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
H304 — May be fatal if swallowed and enters airways (aspiration hazard); H336 — May cause drowsiness or dizziness (narcosis, single exposure) . These are GHS hazard classifications for the raw material, not typical cosmetic exposure
Regulatory Flags
Frequently Asked Questions
Is Tetradecane safe in cosmetics?
H304 — May be fatal if swallowed and enters airways (aspiration hazard); H336 — May cause drowsiness or dizziness (narcosis, single exposure) . These are GHS hazard classifications for the raw material, not typical cosmetic exposure The EU classifies Tetradecane as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Tetradecane allowed in the EU?
Tetradecane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetradecane do in cosmetics?
Tetradecane functions as: Perfuming, solvent, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 629-59-4.
What is the Margin of Safety for Tetradecane?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Tetradecane?
The NOAEL (No Observed Adverse Effect Level) for Tetradecane is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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