Moderate Cosmetic Ingredient NOAEL Data

Thiolactic Acid

INCI: THIOLACTIC ACID

CAS Number
79-42-5
Function
Depilatory, Hair Waving/Straightening, Reducing Agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; general cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Thiolactic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 60 mg/kg bw/day oral rat oral REACH
NOAEL 150 mg/kg bw/day oral rat oral REACH
LOAEL 60 mg/kg bw/day oral rat oral REACH

Expert Verdict

Skin/eye irritant; must comply with the same group restrictions as thioglycolic acid; mandatory label warnings apply

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Thiolactic Acid safe in cosmetics?

Skin/eye irritant; must comply with the same group restrictions as thioglycolic acid; mandatory label warnings apply The EU classifies Thiolactic Acid as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is Thiolactic Acid allowed in the EU?

Thiolactic Acid EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Thiolactic Acid do in cosmetics?

Thiolactic Acid functions as: Depilatory, Hair Waving/Straightening, Reducing Agent. It is classified as a cosmetic ingredient in our database. CAS number: 79-42-5.

What is the Margin of Safety for Thiolactic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Thiolactic Acid?

The NOAEL (No Observed Adverse Effect Level) for Thiolactic Acid is 60 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

๐Ÿ“ฑ

Is Thiolactic Acid in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Thiolactic Acid in your formulation.