Is 5-Methyl-Alpha-Ionone safe in cosmetics?
5-Methyl-Alpha-Ionone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
5-Methyl-Alpha-Ionone
Also known as: Methyl-alpha-ionone, 3-Buten-2-one, 4-(2,5,6,6-tetramethyl-2-cyclohexen-1-yl)-, alpha-Ionone, methyl-, alpha-Ionone, 6-methyl-, 4-(2,5,6,6-Tetramethyl-2-cyclohexen-1-yl)-3-butene-2-one (+11 more)
INCI: 5-METHYL-ALPHA-IONONE
5-Methyl-Alpha-Ionone (CAS 79-69-6) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 79-69-6 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming)
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; IFRA-regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Methyl-Alpha-Ionone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6480 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 5-Methyl-Alpha-Ionone.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Methyl-alpha-ionone
3-Buten-2-one, 4-(2,5,6,6-tetramethyl-2-cyclohexen-1-yl)-
alpha-Ionone, methyl-
alpha-Ionone, 6-methyl-
4-(2,5,6,6-Tetramethyl-2-cyclohexen-1-yl)-3-butene-2-one
6-Methyl-alpha-ionone
BRN 1343498
Cyclocitrylidenebutanone, alpha-
Cyclocitrylidenemethyl ethyl ketone, alpha-
EINECS 201-219-6
FEMA No. 2597
alpha-Inone, methyl-
2,6-cis-(2(1),2(2))-alpha-Ionone, cis-
Methyl alpha-ionone
4-(2,5,6,6-Tetramethyl-2-cyclo-hexen-1-yl)-3-buten-2-one
UNII-O3M0L879K6
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 5-Methyl-Alpha-Ionone allowed in the EU?
5-Methyl-Alpha-Ionone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Methyl-Alpha-Ionone do in cosmetics?
5-Methyl-Alpha-Ionone functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 79-69-6.
Is 5-Methyl-Alpha-Ionone used outside cosmetics?
5-Methyl-Alpha-Ionone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 5-Methyl-Alpha-Ionone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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