Is trans-2-Hexenyl Butyrate safe in cosmetics?
trans-2-Hexenyl Butyrate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
trans-2-Hexenyl Butyrate
INCI: TRANS-2-HEXENYL BUTYRATE
trans-2-Hexenyl Butyrate (CAS 53398-83-7) is a cosmetic cosmetic ingredient functioning as Perfuming / Fragrance ingredient (green, fruity note). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 53398-83-7 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming / Fragrance ingredient (green, fruity note)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[(E)-hex-2-enyl] butanoate
InChIKey
PCGACKLJNBBQGM-VOTSOKGWSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as fragrance; FEMA GRAS (FEMA 3929)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for trans-2-Hexenyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
1375
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
trans-2-HEXENYL BUTANOATE | 2008 | No safety concern at current levels of intake when used as a flavouring agent | ">RS 952-JECFA 69/151 | ">FAS 60-JECFA 69/628
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
trans-2-HEXENYL BUTYRATE | 2008 | No safety concern at current levels of intake when used as a flavouring agent | ">RS 952-JECFA 69/151 | ">FAS 60-JECFA 69/628
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for trans-2-Hexenyl Butyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
(E)-2-HEXENYL BUTYRATE
Food Category
flavoring
Frequently Asked Questions
Is trans-2-Hexenyl Butyrate allowed in the EU?
trans-2-Hexenyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does trans-2-Hexenyl Butyrate do in cosmetics?
trans-2-Hexenyl Butyrate functions as: Perfuming / Fragrance ingredient (green, fruity note). It is classified as a cosmetic ingredient in our database. CAS number: 53398-83-7.
Is trans-2-Hexenyl Butyrate used outside cosmetics?
trans-2-Hexenyl Butyrate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check trans-2-Hexenyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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