Tribenzoin

Also known as: 1,2,3-Propanetriol, 1,2,3-tribenzoate

INCI: TRIBENZOIN

Tribenzoin (CAS 614-33-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.

View industrial chemical safety profile for CAS 614-33-5 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient, skin conditioning
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C24H20O6
MW
404.4 g/mol
EC Number
210-379-6
PubChem CID
61156
IUPAC Name
2,3-dibenzoyloxypropyl benzoate
InChIKey
HIZCTWCPHWUPFU-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted for cosmetic use

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Tribenzoin.

Calculate MoS for your specific formulation with the MoS Calculator.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Regulatory (3)
JECFA Number
861
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
GLYCERYL TRIBENZOATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/112 | FAS 48-JECFA 57/227 (2001)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
TRIBENZOIN | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/112 | FAS 48-JECFA 57/227 (2001)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Deodorizer Flavouring and nutrient Fragrance Plasticizer Softener and conditioner
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Tribenzoin.

Regulatory Flags

potential-allergen fragrance-component fda_food_additive

Known Synonyms

1,2,3-Propanetriol, 1,2,3-tribenzoate

Chemical Function

Deodorizer Softener and conditioner Fragrance Flavouring and nutrient Plasticizer Adhesion/cohesion promoter

Regulatory Lists

Europe food_additive; Substances Added to Food (formerly EAFUS) (2/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical and food safety data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
TRIBENZOIN
ChEMBL ID
CHEMBL6068549
Max Phase
1
View full pharmaceutical profile →
SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
GLYCERYL TRIBENZOATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
View full food safety profile →

Frequently Asked Questions

Is Tribenzoin safe in cosmetics?

Tribenzoin has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Tribenzoin allowed in the EU?

Tribenzoin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tribenzoin do in cosmetics?

Tribenzoin functions as: Fragrance ingredient, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 614-33-5.

Is Tribenzoin used outside cosmetics?

Tribenzoin also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Related Ingredients

2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent Same category
Fragrance
Acetoin
Excellent Same category
Skin conditioning, fragrance
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Ethyl Nicotinate
Moderate Chemical family
Skin conditioning agent (vasodilator ...
p-Cresyl Benzoate
Good Chemical family
Fragrance ingredient
t-Butyl Benzoyl Peroxide
Moderate Chemical family
UV Absorber (per CosIng); organic per...

Is Tribenzoin in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Tribenzoin in your formulation.