Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Pharmacologically active ingredient that causes visible flushing and erythema; contraindicated for sensitive and rosacea-prone skin; concentration must be tightly controlled to avoid drug-cosmetic boundary issues in both EU and US; not suitable for leave-on products at high percentages without established margin of safety.
Frequently Asked Questions
Is Ethyl Nicotinate safe in cosmetics?
Pharmacologically active ingredient that causes visible flushing and erythema; contraindicated for sensitive and rosacea-prone skin; concentration must be tightly controlled to avoid drug-cosmetic boundary issues in both EU and US; not suitable for leave-on products at high percentages without established margin of safety. The EU classifies Ethyl Nicotinate as "restricted". Safety rating: MODERATE.
Is Ethyl Nicotinate allowed in the EU?
Ethyl Nicotinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Nicotinate do in cosmetics?
Ethyl Nicotinate functions as: Skin conditioning agent (vasodilator / rubefacient). It is classified as a cosmetic ingredient in our database. CAS number: 614-18-6.
What is the Margin of Safety for Ethyl Nicotinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Ethyl Nicotinate compliance across multiple jurisdictions:
Related Ingredients
Is Ethyl Nicotinate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethyl Nicotinate in your formulation.