Good Cosmetic Ingredient NOAEL Data GHS Classified

TRIFLUOROACETIC ACID

CAS Number
76-05-1
Function
Ph Adjusters
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for TRIFLUOROACETIC ACID. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 0.05 mg/L air other code:3544 inhalation REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
corr; cancer;health haz
Hazard Statements
Causes severe skin burns and eye damage Causes damage to respiratory tract if inhaled Harmful to aquatic life
Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of fumes may cause lung oedema. See Notes.
Routes of Exposure
Serious local effects by all routes of exposure.

Expert Verdict

TRIFLUOROACETIC ACID is listed in the EU CosIng database with functions: Ph Adjusters It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment

Frequently Asked Questions

Is TRIFLUOROACETIC ACID safe in cosmetics?

TRIFLUOROACETIC ACID is listed in the EU CosIng database with functions: Ph Adjusters It is permitted in the EU without specific restrictions. The EU classifies TRIFLUOROACETIC ACID as "Permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is TRIFLUOROACETIC ACID allowed in the EU?

TRIFLUOROACETIC ACID EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does TRIFLUOROACETIC ACID do in cosmetics?

TRIFLUOROACETIC ACID functions as: Ph Adjusters. It is classified as a cosmetic ingredient in our database. CAS number: 76-05-1.

What is the NOAEL for TRIFLUOROACETIC ACID?

The NOAEL (No Observed Adverse Effect Level) for TRIFLUOROACETIC ACID is 0.05 mg/L air based on a inhalation study via other route in code:3544. Source: REACH.

Is TRIFLUOROACETIC ACID classified as hazardous under GHS?

TRIFLUOROACETIC ACID carries a GHS signal word of "DANGER". Hazard statements: Causes severe skin burns and eye damage Causes damage to respiratory tract if inhaled Harmful to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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