Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Valeraldehyde

INCI: VALERALDEHYDE (SYNONYM: PENTANAL)

CAS Number
110-62-3
Function
Fragrance ingredient, flavoring agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS (No. 3098); permitted in cosmetics and food flavorings

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Valeraldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 1000 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour.

Expert Verdict

H225 highly flammable; H317 skin sensitizer; H319 serious eye irritation; H332 harmful if inhaled. Suspected carcinogenicity flagged for NTP review. Severe skin/eye irritant at concentrated levels

โš ๏ธ
Concern Level: High

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Valeraldehyde safe in cosmetics?

H225 highly flammable; H317 skin sensitizer; H319 serious eye irritation; H332 harmful if inhaled. Suspected carcinogenicity flagged for NTP review. Severe skin/eye irritant at concentrated levels The EU classifies Valeraldehyde as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Valeraldehyde allowed in the EU?

Valeraldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Valeraldehyde do in cosmetics?

Valeraldehyde functions as: Fragrance ingredient, flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-62-3.

What is the Margin of Safety for Valeraldehyde?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Valeraldehyde?

The NOAEL (No Observed Adverse Effect Level) for Valeraldehyde is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

๐Ÿ“ฑ

Is Valeraldehyde in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Valeraldehyde in your formulation.