Is Valeraldehyde safe in cosmetics?
Valeraldehyde has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Valeraldehyde
Also known as: n-Pentanal, 4-01-00-03268, BRN 1616304, EINECS 203-784-4, FEMA No. 3098 (+13 more)
INCI: VALERALDEHYDE (SYNONYM: PENTANAL)
Valeraldehyde (CAS 110-62-3) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, flavoring agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 110-62-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Valeraldehyde is classified GHS Danger (H225, H315, H317, H319, H332, H335, H303, H313) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance ingredient, flavoring agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
pentanal
InChIKey
HGBOYTHUEUWSSQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FEMA GRAS (No. 3098); permitted in cosmetics and food flavorings
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Valeraldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1350 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
1417
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
Vapor may irritate eyes. | Valeraldehyde can affect you when breathed in. Contact can severely irritate the eyes, skin, nose and throat. ...
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (2)
JECFA Number
89
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
VALERALDEHYDE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/29 | FAS 40-JECFA 49/147
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Valeraldehyde.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
n-Pentanal
4-01-00-03268
BRN 1616304
EINECS 203-784-4
FEMA No. 3098
FEMA Number 3098
UNII-B975S3014W
1-Pentanal
Amylaldehyde
FEMA 3098
N-C4H9CHO
N-Valeraldehyde, 8CI
N-Valeric aldehyde
PNO
Pentan-1-al
Pentanal (valeraldehyde)
Pentyl aldehyde
Valeraldehyde [UN2058] [Flammable liquid]
Chemical Function
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
air; Cons electronics mech appliances and machinery; detected; emissions; Europe
air; Cons electronics mech appliances and machinery; detected; emissions; Europe
Cons electronics mech appliances and machinery; detected; emissions; Europe
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Other direct contact consumer goods
air; Cons electronics mech appliances and machinery; detected; emissions; Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PENTANAL
ChEMBL ID
CHEMBL18602
Frequently Asked Questions
Is Valeraldehyde allowed in the EU?
Valeraldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Valeraldehyde do in cosmetics?
Valeraldehyde functions as: Fragrance ingredient, flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-62-3.
Is Valeraldehyde used outside cosmetics?
Valeraldehyde also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Valeraldehyde have different safety status in cosmetics vs industrial chemicals?
Valeraldehyde is classified GHS Danger (H225, H315, H317, H319, H332, H335, H303, H313) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Valeraldehyde compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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