Poor Cosmetic Ingredient GHS Classified

Vinyl Cyclohexene Dioxide

INCI: 4-VINYL-1-CYCLOHEXENE DIEPOXIDE

CAS Number
106-87-6
Function
Industrial epoxy resin diluent
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes Not approved for cosmetics. California Prop 65 listed carcinogen and reproductive toxicant. NTP reasonably anticipated to be a human carcinogen.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. Exposure at high levels could cause death. The effects may be delayed. Medical observation is indicated. See Notes.
Long-term Exposure Effects
The substance may have effects on the kidneys, ovary and testes. This may result in tissue lesions. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Expert Verdict

Confirmed animal carcinogen with clear evidence of squamous cell carcinomas in rats and mice via dermal exposure. Reproductive toxicant causing ovarian and testicular atrophy. Mutagenic with positive Ames test results. Immunosuppressive, nephrotoxic, and classified as IARC Group 2B. NTP reasonably anticipated human carcinogen. Prohibited for cosmetic use.

⚠️
Concern Level: High

Regulatory Flags

prop65 eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Vinyl Cyclohexene Dioxide safe in cosmetics?

Confirmed animal carcinogen with clear evidence of squamous cell carcinomas in rats and mice via dermal exposure. Reproductive toxicant causing ovarian and testicular atrophy. Mutagenic with positive Ames test results. Immunosuppressive, nephrotoxic, and classified as IARC Group 2B. NTP reasonably anticipated human carcinogen. Prohibited for cosmetic use. The EU classifies Vinyl Cyclohexene Dioxide as "prohibited". Safety rating: POOR.

Is Vinyl Cyclohexene Dioxide allowed in the EU?

Vinyl Cyclohexene Dioxide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Vinyl Cyclohexene Dioxide do in cosmetics?

Vinyl Cyclohexene Dioxide functions as: Industrial epoxy resin diluent. It is classified as a cosmetic ingredient in our database. CAS number: 106-87-6.

What is the Margin of Safety for Vinyl Cyclohexene Dioxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Vinyl Cyclohexene Dioxide compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Lygodium Japonicum Spore
Moderate
Disodium Tetrapropenyl Succinate
Moderate
PPG-12/SMDI Copolymer
Moderate
Polysilicone-16
Moderate
2-Hydroxypropyl Acrylate
Poor
Browse all 30,000+ ingredients →
📱

Is Vinyl Cyclohexene Dioxide in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Vinyl Cyclohexene Dioxide in your formulation.

Ingredient Decoder MoS Calculator