Moderate Cosmetic Ingredient NOAEL Data

ZINC FORMALDEHYDE SULFOXYLATE

Also known as: Zinc, bis[1-​(hydroxy-​κO)​methanesulfinato-​κO]​-​, (T-​4)​-, Zinc formaldehydesulfoxylate, Zinc, bis(hydroxymethanesulfinato-OS,O1)-, (T-4)-, Zinc, bis[(hydroxy-κO)methanesulfinato-κO]-, (T-4)-, Methanesulfinic acid, hydroxy-, zinc complex (+12 more)

ZINC FORMALDEHYDE SULFOXYLATE (CAS 24887-06-7) is a cosmetic cosmetic ingredient functioning as Reducing. NOAEL 31.52 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max III/24. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 24887-06-7 →

Auto-generated CPSR Part A draft with source citations
Function
Reducing
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C2H6O6S2Zn
MW
255.6 g/mol
EC Number
246-515-6
PubChem CID
159978
IUPAC Name
zinc hydroxymethanesulfinate
InChIKey
CAAIULQYGCAMCD-UHFFFAOYSA-L

Regulatory Status

EU EU Status restricted
EU Max Conc. III/24
US US Status Not specifically regulated

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for ZINC FORMALDEHYDE SULFOXYLATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =300 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =1000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for ZINC FORMALDEHYDE SULFOXYLATE across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Reducing agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for ZINC FORMALDEHYDE SULFOXYLATE.

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to ZINC FORMALDEHYDE SULFOXYLATE by CAS number or substance name.

Studies
2
Lowest NOAEL
300 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Zinc, bis[1-​(hydroxy-​κO)​methanesulfinato-​κO]​-​, (T-​4)​- Zinc formaldehydesulfoxylate Zinc, bis(hydroxymethanesulfinato-OS,O1)-, (T-4)- Zinc, bis[(hydroxy-κO)methanesulfinato-κO]-, (T-4)- Methanesulfinic acid, hydroxy-, zinc complex Blankit D C.I. Reducing Agent 6 Decroline Decroline Soluble Conc. Decroline soluble Methanesulfinic acid, hydroxy-, zinc salt (2:1) Parolite Protolin SX Redol ZB Redusol Z Safolin EINECS No.: 246-515-6

Chemical Function

Reducing agent

Regulatory Lists

Indirect additives food contact (10/2018)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is ZINC FORMALDEHYDE SULFOXYLATE safe in cosmetics?

ZINC FORMALDEHYDE SULFOXYLATE has a safety rating of "MODERATE" in our database. EU status: restricted. 2 toxicological study endpoint(s) are available in our database.

Is ZINC FORMALDEHYDE SULFOXYLATE allowed in the EU?

ZINC FORMALDEHYDE SULFOXYLATE EU regulatory status: restricted. Maximum allowed concentration: III/24. This is based on EU Regulation 1223/2009 and its amendments.

What does ZINC FORMALDEHYDE SULFOXYLATE do in cosmetics?

ZINC FORMALDEHYDE SULFOXYLATE functions as: Reducing. It is classified as a cosmetic ingredient in our database. CAS number: 24887-06-7.

What is the NOAEL for ZINC FORMALDEHYDE SULFOXYLATE?

The NOAEL (No Observed Adverse Effect Level) for ZINC FORMALDEHYDE SULFOXYLATE is =300 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is ZINC FORMALDEHYDE SULFOXYLATE used outside cosmetics?

ZINC FORMALDEHYDE SULFOXYLATE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does ZINC FORMALDEHYDE SULFOXYLATE have different safety status in cosmetics vs industrial chemicals?

ZINC FORMALDEHYDE SULFOXYLATE is classified GHS CMR hazard (H302, H319, H341, H412) in the chemicals database but is restricted in EU cosmetics at max III/24.

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