Zingiber Officinale Root Extract
INCI: ZINGIBER OFFICINALE ROOT EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Zingiber Officinale Root Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 100 mg/kg bw/day | oral | mouse | Subchronic | COSMOS_DB |
| NOAEL | 100 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| dose_tested | 100 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| dose_tested | 1000 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
Expert Verdict
Zingiber Officinale Root Extract is a well-tolerated botanical with skin conditioning and antioxidant properties; CIR concluded safe in cosmetics at ≤0.2% leave-on when formulated to be non-sensitizing (December 2022).
Regulatory Flags
Frequently Asked Questions
Is Zingiber Officinale Root Extract safe in cosmetics?
Zingiber Officinale Root Extract is a well-tolerated botanical with skin conditioning and antioxidant properties; CIR concluded safe in cosmetics at ≤0.2% leave-on when formulated to be non-sensitizing (December 2022). The EU classifies Zingiber Officinale Root Extract as "permitted". Safety rating: GOOD. 5 toxicological study endpoint(s) are available in our database.
Is Zingiber Officinale Root Extract allowed in the EU?
Zingiber Officinale Root Extract EU regulatory status: permitted. Maximum allowed concentration: ≤0.2% (leave-on); fragrance allergens require labeling above 10 ppm (rinse-off) or 100 ppm (leave-on). This is based on EU Regulation 1223/2009 and its amendments.
What does Zingiber Officinale Root Extract do in cosmetics?
Zingiber Officinale Root Extract functions as: Skin Conditioning, Fragrance, Tonic. It is classified as a Cosmetic Ingredient in our database. CAS number: 84696-15-1.
What is the Margin of Safety for Zingiber Officinale Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Zingiber Officinale Root Extract?
The NOAEL (No Observed Adverse Effect Level) for Zingiber Officinale Root Extract is 100 mg/kg bw/day based on a Subchronic study via oral route in mouse. A total of 5 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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