Good Cosmetic Ingredient NOAEL Data

ZIRCONIUM DIOXIDE

CAS Number
1314-23-4
Function
Opacifying
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for ZIRCONIUM DIOXIDE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3156 mg/kg bw/day oral rat oral REACH
NOAEL 3156 mg/kg bw/day oral rat oral REACH

Expert Verdict

ZIRCONIUM DIOXIDE is listed in the EU CosIng database with functions: Opacifying It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment

Frequently Asked Questions

Is ZIRCONIUM DIOXIDE safe in cosmetics?

ZIRCONIUM DIOXIDE is listed in the EU CosIng database with functions: Opacifying It is permitted in the EU without specific restrictions. The EU classifies ZIRCONIUM DIOXIDE as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is ZIRCONIUM DIOXIDE allowed in the EU?

ZIRCONIUM DIOXIDE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does ZIRCONIUM DIOXIDE do in cosmetics?

ZIRCONIUM DIOXIDE functions as: Opacifying. It is classified as a cosmetic ingredient in our database. CAS number: 1314-23-4.

What is the NOAEL for ZIRCONIUM DIOXIDE?

The NOAEL (No Observed Adverse Effect Level) for ZIRCONIUM DIOXIDE is 3156 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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