Good Cosmetic Ingredient NOAEL Data

2,5-XYLENOL

CAS Number
95-87-4
Function
Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

3 study endpoints found for 2,5-XYLENOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 100 mg/kg bw/day oral - oral REACH
NOEL 30 mg/kg bw/day oral rat oral REACH
NOAEL 100 mg/kg bw/day oral rat oral REACH

Expert Verdict

2,5-XYLENOL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is 2,5-XYLENOL safe in cosmetics?

2,5-XYLENOL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies 2,5-XYLENOL as "Permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is 2,5-XYLENOL allowed in the EU?

2,5-XYLENOL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,5-XYLENOL do in cosmetics?

2,5-XYLENOL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 95-87-4.

What is the NOAEL for 2,5-XYLENOL?

The NOAEL (No Observed Adverse Effect Level) for 2,5-XYLENOL is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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