2,5-XYLENOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
3 study endpoints found for 2,5-XYLENOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
| NOEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
2,5-XYLENOL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is 2,5-XYLENOL safe in cosmetics?
2,5-XYLENOL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies 2,5-XYLENOL as "Permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is 2,5-XYLENOL allowed in the EU?
2,5-XYLENOL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,5-XYLENOL do in cosmetics?
2,5-XYLENOL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 95-87-4.
What is the NOAEL for 2,5-XYLENOL?
The NOAEL (No Observed Adverse Effect Level) for 2,5-XYLENOL is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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