Poor Cosmetic Ingredient SCCS/CIR Reviewed

2,4-Diaminophenol

INCI: 2,4-DIAMINOPHENOL

CAS Number
95-86-3
Function
Oxidative hair dye coupler
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: Safe for use in hair dyes at โ‰ค0.2% as free base; coal tar hair dye exemption applies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir York 0 1994
Verdict: unknown

Expert Verdict

Prohibited in EU Annex II; mutagenic concerns; limited to hair dye use in the US

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Concern Level: High

Frequently Asked Questions

Is 2,4-Diaminophenol safe in cosmetics?

Prohibited in EU Annex II; mutagenic concerns; limited to hair dye use in the US The EU classifies 2,4-Diaminophenol as "prohibited". Safety rating: POOR. This ingredient has been reviewed by cir.

Is 2,4-Diaminophenol allowed in the EU?

2,4-Diaminophenol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,4-Diaminophenol do in cosmetics?

2,4-Diaminophenol functions as: Oxidative hair dye coupler. It is classified as a cosmetic ingredient in our database. CAS number: 95-86-3.

What is the Margin of Safety for 2,4-Diaminophenol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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