Is 2-Furylmethanethiol safe in cosmetics?
2-Furylmethanethiol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
2-Furylmethanethiol
Also known as: 2-Furanmethanethiol, 2-Furfurylthiol, 2-Furylmethylthiol, Furan-2-ylmethanethiol, Furfuryl mercaptan (+15 more)
INCI: 2-FURYLMETHANETHIOL
2-Furylmethanethiol (CAS 98-02-2) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (sulfur-containing furanyl compound); primarily a. NOAEL 3 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 98-02-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient (sulfur-containing furanyl compound); primarily a flavoring agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
furan-2-ylmethanethiol
InChIKey
ZFFTZDQKIXPDAF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA-recognized as GRAS flavoring agent; not specifically restricted for cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Furylmethanethiol.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for 2-Furylmethanethiol across SCCS product categories, with measured dermal absorption where available.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (4)
JECFA Number
1072
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-FURYLMETHANETHIOL | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/81 | FAS 50-JECFA 59/299
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
alpha-FURFURYL MERCAPTAN | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/81 | FAS 50-JECFA 59/299
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
FURFURYL MERCAPTAN | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/81 | FAS 50-JECFA 59/299
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 2-Furylmethanethiol.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
2-Furanmethanethiol
2-Furfurylthiol
2-Furylmethylthiol
Furan-2-ylmethanethiol
Furfuryl mercaptan
Furfurylthiol
2-furilmetanotiol
FURAN, 2-METHYLTHIOL-
FURFURYL-MERCAPTANE
5-17-03-00351
BRN 0383594
EINECS 202-628-2
FEMA No. 2493
(2-Furanyl)methylmercaptan
Furfuryl thiol
2-Furfurylmercaptan
2-Furylmethyl mercaptan
2-(Mercaptomethyl)furan
NSC 41142
UNII-29W096TCPG
Chemical Function
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
Europe
Australia; Food and drug - smoking-related products
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3560314
Frequently Asked Questions
Is 2-Furylmethanethiol allowed in the EU?
2-Furylmethanethiol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Furylmethanethiol do in cosmetics?
2-Furylmethanethiol functions as: Fragrance ingredient (sulfur-containing furanyl compound); primarily a flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 98-02-2.
Is 2-Furylmethanethiol used outside cosmetics?
2-Furylmethanethiol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Furylmethanethiol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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