Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for 2-Furylmethanethiol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 3 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Thiols are reactive with skin proteins, presenting a sensitization concern. Strong pungent odor limits practical use levels in cosmetics. Primarily used in food flavoring rather than leave-on cosmetics. The furan ring adds metabolic activation considerations.
Regulatory Flags
Frequently Asked Questions
Is 2-Furylmethanethiol safe in cosmetics?
Thiols are reactive with skin proteins, presenting a sensitization concern. Strong pungent odor limits practical use levels in cosmetics. Primarily used in food flavoring rather than leave-on cosmetics. The furan ring adds metabolic activation considerations. The EU classifies 2-Furylmethanethiol as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is 2-Furylmethanethiol allowed in the EU?
2-Furylmethanethiol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Furylmethanethiol do in cosmetics?
2-Furylmethanethiol functions as: Fragrance ingredient (sulfur-containing furanyl compound); primarily a flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 98-02-2.
What is the Margin of Safety for 2-Furylmethanethiol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Furylmethanethiol?
The NOAEL (No Observed Adverse Effect Level) for 2-Furylmethanethiol is 3 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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